Volume 19, Issue 9, September 2019, Page 54-56.

IntroductionDeep brain stimulation (DBS) is increasingly used to treat the symptoms of various neurologic and psychiatric conditions. People can undergo the procedure during reproductive years but the safety of DBS in pregnancy remains relatively unknown given the paucity of published cases. We thus conducted a review of the literature to determine the state of current knowledge about DBS in pregnancy and to determine how eligibility criteria are approached in clinical trials with respect to pregnancy and the potential for pregnancy.MethodsA literature (...) review was conducted in EMBASE to identify articles involving DBS and pregnancy. Two reviewers independently analyzed the articles to confirm inclusion. Data extracted for analysis included conditions treated, complications at all stages of pregnancy, neonatal/pediatric outcomes, and DBS target. A second search was then conducted using www.clinicaltrials.gov. The same two reviewers then assessed whether each trial excluded pregnant individuals, lactating individuals, or persons of childbearing age planning to conceive. Also assessed was whether contraception had to be deemed adequate prior to enrollment.ResultsThe literature search returned 681 articles. Following independent analysis and agreement of two reviewers, 8 pregnancy related DBS articles were included for analysis. These articles described 27 subjects, 29 pregnancies (2 with subsequent pregnancies), and 31 infants (2 twin pregnancies). There was 1 preterm birth at 35 weeks, and 3 patients who experienced discomfort from the DBS battery (i.e., impulse generator) placement site. All 27 patients had a DBS device implanted before they became pregnant, which remained in use throughout their pregnancy. There was exclusion of pregnant individuals from 68% of 135 interventional trials involving DBS. Approximately 44% of these trials excluded persons of childbearing age not on “adequate contraception” or wishing to conceive in the coming years. Finally, 22% excluded breastfeeding persons.ConclusionThe data from 29 pregnancies receiving DBS treatment during pregnancy was not associated with unexpected pregnancy or post-partum complication patterns. Many clinical trials have excluded pregnant individuals. Documentation of outcomes in larger numbers of pregnancies will help clarify the safety profile and will help guide study designs that will safely include pregnant patients. (shrink)

The relationship of consciousness to brain, which Schopenhauer grandly referred to as the "world knot," remains an unsolved problem within both philosophy and science. The central focus in what follows is the relevance of science---from psychoanalysis to neurophysiology and quantum physics-to the mind-brain puzzle. Many would argue that we have advanced little since the age of the Greek philosophers, and that the extraordinary accumulation of neuroscientific knowledge in this century has helped not at all. Increas- ingly, philosophers and scientists have (...) tended to go their separate ways in considering the issues, since they tend to differ in the questions that they ask, the data and ideas which are provided for consideration, their methods for answering these questions, and criteria for judging the acceptability of an answer. But it is our conviction that philosophers and scientists can usefully interchange, at least to the extent that they provide co~straints upon each other’s preferred strategies, and it may prove possible for more substantive progress to be made. Philosophers have said some rather naive things by ignoring the extraordinary advances in the neurosciences in the twentieth century. The skull is not filled with green cheese! On the other hand, the arrogance of many scientists toward philosophy and their faith in the scientific method is equally naive. Scientists clearly have much to learn from philosophy as an intellectual discipline. Manifestations of Mind: Some Conceptual and Empirical Issues Walter B. Weimer Pages 5-31 The Mysterious “Split‘: A Clinical Inquiry into Problems of Consciousness and Brain Peter H. Knapp Pages 37-69 Mind, Brain, and the Symbolic Consciousness Irwin Savodnik Pages 73-98 Brain and Free Will John C. Eccles Pages 101-121 An Old Ghost in a New Body C. Wade Savage Pages 125-153 How Dogmatic Can Materialism Be? John C. Eccles Pages 155-160 Mental Phenomena as Causal Determinants in Brain Function R. W. Sperry Pages 163-177 Consciousness as an Emergent Causal Agent in the Context of Control System Theory E. M. Dewan Pages 181-198 Reductionism, Levels of Organization, and the Mind-Body Problem William C. Wimsatt Pages 205-267 Mind, Structure, and Contradiction Gordon G. Globus Pages 271-293 Problems Concerning the Structure of Consciousness Karl H. Pribram Pages 297-313 The Role of Scientific Results in Theories of Mind and Brain: A Conversation among Philosophers and Scientists E. M. Dewan, John C. Eccles, Gordon G. Globus, Keith Gunderson, Peter H. Knapp, Grover Maxwell et al. Pages 317-328 Scientific Results and the Mind-Brain Issue: Some Afterthoughts Grover Maxwell Pages 329-358. (shrink)

Alterity, the difference that being-other makes, is not an overt theme in the writing of Ueda Shizuteru, and yet by bringing alterity to the fore we are able to connect and examine several themes that Ueda does engage explicitly. It will turn out that several models of alterity are discernable in Ueda’s philosophy, and their common ground opens a mode of being-other that offers an alternative to dominant models of irreducible difference. Ueda’s philosophy of language suggests four alternative configurations that (...) increasingly allow for the dual emergence of authentic otherness and selfhood. Those configurations are intimated in his interpretations of Nishida’s pure experience, of the interplay of language and silence, of a dialogue envisioned in a Zen oxherding picture, and of the poetic form known as linked verse, which best models how discrete beings help create a world in common. (shrink)

Structural realism as developed by John Worrall and others can claim philosophical roots as far back as the late 19th century, though the discussion at that time does not unambiguously favor the contemporary form, or even its realism. After a critical examination of some aspects of the historical background some severe critical challenges to both Worrall's and Ladyman's versions are highlighted, and an alternative empiricist structuralism proposed. Support for this empiricist version is provided in part by the different way (...) in which we can do justice to Worrall's original demands and in part by the viewpoint it provides (in contrast to e.g. Michael Friedman's) on the stability maintained through scientific theory change. Planck against the heretics 1.1 Poincaré on the meaning of Maxwell's equations 1.2 Two responses: reification and structuralism On the road to structuralism 2.1 The microscope 2.2 Mathematization of the world picture 2.3 The 18th–20th century The new structural realism 3.1 From scientific realism to structuralism 3.2 The Ladyman variant: objectivity and invariance 3.3 How is structural realism supported? An empiricist structuralism 4.1 Royal succession in science 4.2 Defence of the empiricist version 4.3 Structure: an empiricist view. (shrink)

Realism about computation is the view that whether or not a particular physical system is performing a particular computation is at least sometimes a mindindependent feature of reality. The caveat ’at least sometimes’ is necessary here because a realist about computation need not believe that all instances of computation should be realistically construed. The computational theory of mind presupposes realism about computation. If whether or not the human nervous system implements particular computations is not a natural fact about the world (...) that is independent of whether we represent it as doing so, then the computational theory of mind fails to naturalise the mind. Realism about computation is also presupposed by attempts to use computational principles such as Landauer’s Principle to dispel Maxwell’s Demon. Realism about computation has been challenged by Hilary Putnam and John Searle among others. Various arguments have been put forward purporting to show that any physical system of sufficient complexity trivially implements all computations. Ladyman et al. offer a precisification and general proof Landauer’s Principle. In order to do this they present an analysis of what it is for a physical process to implement a logical transformation. In this paper, their analysis is explained and its implications for realism about computation and the use of Landauer’s Principle in foundational debates is assessed. (shrink)

Peter Abelard (1079–1142 ce) was the most wide‐ranging philosopher of the twelfth century. He quickly established himself as a leading teacher of logic in and near Paris shortly after 1100. After his affair with Heloise, and his subsequent castration, Abelard became a monk, but he returned to teaching in the Paris schools until 1140, when his work was condemned by a Church Council at Sens. His logical writings were based around discussion of the “Old Logic”: Porphyry's Isagoge, aristotle'S Categories and (...) On Interpretation and boethius'S textbook on topical inference. They comprise a freestanding Dialectica (“Logic”; probably c.1116), a set of commentaries (known as the Logica [Ingredientibus], c. 1119) and a later (c. 1125) commentary on the Isagoge (Logica Nostrorum Petititoni Sociorum or Glossulae). In a work Abelard called his Theologia, issued in three main versions (between 1120 and c.1134), he attempted a logical analysis of trinitarian relations and explored the philosophical problems surrounding God's claims to omnipotence and omniscience. The Collationes (“Debates,” also known as “Dialogue between a Christian, a Philosopher and a Jew”; probably c.1130) present a rational investigation into the nature of the highest good, in which the Christian and the Philosopher (who seems to be modeled on a philosopher of pagan antiquity) are remarkably in agreement. The unfinished Scito teipsum (“Know thyself,” also known as the “Ethics”; c.1138) analyses moral action. (shrink)

In evolutionary biology, niche construction is sometimes described as a genuine evolutionary process whereby organisms, through their activities and regulatory mechanisms, modify their environment such as to steer their own evolutionary trajectory, and that of other species. There is ongoing debate, however, on the extent to which niche construction ought to be considered a bona fide evolutionary force, on a par with natural selection. Recent formulations of the variational free-energy principle as applied to the life sciences describe the properties of (...) living systems, and their selection in evolution, in terms of variational inference. We argue that niche construction can be described using a variational approach. We propose new arguments to support the niche construction perspective, and to extend the variational approach to niche construction to current perspectives in various scientific fields. (shrink)

When von Neumann's and Morgenstern's Theory of Games and Economic Behavior appeared in 1944, one thought that a complete theory of strategic social behavior had appeared out of nowhere. However, game theory has, to this very day, remained a fast-growing assemblage of models which have gradually been united in a new social theory - a theory that is far from being completed even after recent advances in game theory, as evidenced by the work of the three Nobel Prize winners, (...) class='Hi'>John F. Nash, John C. Harsanyi, and Reinhard Selten. Two of them, Harsanyi and Selten, have contributed important articles to the present volume. This book leaves no doubt that the game-theoretical models are on the right track to becoming a respectable new theory, just like the great theories of the twentieth century originated from formerly separate models which merged in the course of decades. For social scientists, the age of great discover ies is not over. The recent advances of today's game theory surpass by far the results of traditional game theory. For example, modem game theory has a new empirical and social foundation, namely, societal experiences; this has changed its methods, its "rationality. " Morgenstern (I worked together with him for four years) dreamed of an encompassing theory of social behavior. With the inclusion of the concept of evolution in mathematical form, this dream will become true. Perhaps the new foundation will even lead to a new name, "conflict theory" instead of "game theory. (shrink)

This book presents the first detailed history of the modern passport and why it became so important for controlling movement in the modern world. It explores the history of passport laws, the parliamentary debates about those laws, and the social responses to their implementation. The author argues that modern nation-states and the international state system have 'monopolized the 'legitimate means of movement',' rendering persons dependent on states' authority to move about - especially, though not exclusively, across international boundaries. This new (...) edition reviews other scholarship, much of which was stimulated by the first edition, addressing the place of identification documents in contemporary life. It also updates the story of passport regulations from the publication of the first edition, which appeared just before the terrorist attacks of 9/11, to the present day. (shrink)

This is a paperback edition of a major contribution to the field, first published in hard covers in 1977. The book outlines a general theory of rational behaviour consisting of individual decision theory, ethics, and game theory as its main branches. Decision theory deals with a rational pursuit of individual utility; ethics with a rational pursuit of the common interests of society; and game theory with an interaction of two or more rational individuals, each pursuing his own interests in a (...) rational manner. (shrink)

The relation between body and mind is one of the oldest riddles that has puzzled mankind. That material and mental events may interact is accepted even by the law: our mental capacity to concentrate on the task can be seriously reduced by drugs. Physical and chemical processes may act upon the mind; and when we are writing a difficult letter, our mind acts upon our body and, through a chain of physical events, upon the mind of the recipient of the (...) letter. This is what the authors of this book call the 'interaction of mental and physical events'. We know very little about this interaction; and according to recent philosophical fashions this is explained by the alleged fact that we have brains but no thoughts. The authors of this book stress that they cannot solve the body mind problem; but they hope that they have been able to shed new light on it. Eccles especially with his theory that the brain is a detector and amplifier; a theory that has given rise to important new developments, including new and exciting experiments; and Popper with his highly controversial theory of 'World 3'. They show that certain fashionable solutions which have been offered fail to understand the seriousness of the problems of the emergence of life, or consciousness and of the creativity of our minds. In Part I, Popper discusses the philosophical issue between dualist or even pluralist interaction on the one side, and materialism and parallelism on the other. There is also a historical review of these issues. In Part II, Eccles examines the mind from the neurological standpoint: the structure of the brain and its functional performance under normal as well as abnormal circumstances. The result is a radical and intriguing hypothesis on the interaction between mental events and detailed neurological occurrences in the cerebral cortex. Part III, based on twelve recorded conversations, reflects the exciting exchange between the authors as they attempt to come to terms with their opinions. (shrink)

What role does language play during attention allocation in perceiving and remembering events? We recorded adults‟ eye movements as they studied animated motion events for a later recognition task. We compared native speakers of two languages that use different means of expressing motion (Greek and English). In Experiment 1, eye movements revealed that, when event encoding was made difficult by requiring a concurrent task that did not involve language (tapping), participants spent extra time studying what their language treats as the (...) details of the event. This „linguistic encoding‟ effect was eliminated both when event encoding was made easier (no concurrent task) and when the concurrent task required the use of language (counting aloud). In Experiment 2, under conditions of a delayed concurrent task of counting aloud, participants used language covertly just prior to engaging in the additional task. Together, the results indicate that language can be optionally recruited for encoding events, especially under conditions of high cognitive load. Yet, these effects are malleable and flexible and do not appear to shape core biases in event perception and memory. (shrink)

This is the correspondence (1959–1969), on the nature of the evolutionary process, between the biologist Theodosius Dobzhansky and the historian John C. Greene.

Preface.--Science, ideology, and world view.--Objectives and methods in intellectual history.--The Kuhnian paradigm and the Darwinian revolution in natural history.--Biology and social theory in the nineteenth century.--Darwin as a social evolutionist.--Darwinism as a world view.--From Huxley to Huxley.--Postscript.

The first of 3 volumes of essays on Japanese philosophy, this work brings together essays that clarify its heritage and its practice, above all in the dynamic thought of Nishida Kitaro. Showing how philosophy takes shape through the translation of language and culture, the author examines the frameworks that have defined and confined Nishida’s thought and then charts new avenues of questioning Nishida and letting him question us. How should we envision the world at a time of environmental crisis, how (...) might we rethink our conceptions of history, religion and God; how is bodily awareness a way that the world knows itself, and just what can we make of Nishida'™s famous notion of nothingness—these are some of the questions that guide the meticulous explorations in this collection. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Revolutionary Christianity: The 1966 South American Lectures by John Howard Yoder, and: John Howard Yoder: Spiritual Writings by John Howard YoderJohn C. ShelleyRevolutionary Christianity: The 1966 South American Lectures John Howard Yoder. Edited by Paul Martens, Mark Thiessen Nation, Matthew Porter, and Myles Werntz eugene, or: cascade books, 2011. 193 pp. $18.00John Howard Yoder: Spiritual Writings John Howard Yoder. Selected with an Introduction (...) by Paul Martens and Jenny Howell. Modern Spiritual Masters Series maryknoll, ny: orbis, 2011. 172 pp. $20.00For more than sixteen years after his death in late 1997, John Howard Yoder has provoked, challenged, and inspired a new generation of theologians, ethicists, and pastors—including the editors of these two volumes—many of whom never met Yoder nor heard him speak. Now, just as this new generation prepares to preserve and enlarge his legacy, a series of revelations detailing Yoder’s repugnant behavior against women and against administrators of the Anabaptist Mennonite Biblical Seminary (AMBS) in Elkhart, Indiana, compromises that legacy. It has been widely known that in 1992, after some initial resistance, Yoder submitted to a disciplining process initiated by his home congregation for inappropriate advances to women and that he had been reconciled and reunited in worship shortly before his death.1 The new allegations, which have become broadly public only since 2013, are considerably more serious and include coercive—indeed, “violent”—advances toward a number of women over three decades, including many students and others in subordinate positions. Further, Yoder abused the power of his reputation by intimidating the president and other administrators of AMBS, compelling them to keep the matter quiet as he slipped away to a more prestigious appointment at Notre Dame in 1984.2 According to some witnesses, this inappropriate behavior continued at Notre Dame. [End Page 210]These revelations have complicated the process of writing even a simple review.3 Were Yoder an astrophysicist with groundbreaking discoveries regarding dark matter, we would be disappointed with his behavior, but we would not challenge on those grounds the veracity of his discovery. With Christian ethics, the issue is more complicated, especially for someone of Yoder’s stature whose persona suggested that he was committed to and embodied, however imperfectly, what he proclaimed. Reading these volumes a second time has brought several jarring moments. For example, in both volumes, Yoder defines in almost identical language the temptation of “egocentric altruism”:The real temptation of good people like us is not the crude, the crass, and the carnal as those traits are defined in Puritanism. The real refined temptation, with which Jesus himself was tried, was that of egocentric altruism, of being oneself the incarnation of a good and righteous cause for which others are to suffer, of stating our self-justification in the form of a duty to others.(Revolutionary Christianity, 83; Essential Writings, 144)Consider also the following statement on religious liberty, which is certainly prescient in view of the current conflicts being played out in the courts: “Religious liberty is not only a necessary limitation upon the power of the state; it also marks a voluntary renunciation by the church of any capacity to coerce” (Revolutionary Christianity, 11). At the very least, then, perhaps we should read Yoder’s misdeeds as a warning: even we may be tempted by the crude and the carnal as well as by egocentric altruism; when threatened, even we may resort to coercion.The fourteen lectures in Revolutionary Christianity, published here for the first time, are organized into three sections—“The Believers Church,” “Peace,” and “Church in a Revolutionary World”—roughly the order of presentation to predominantly Mennonite and Anabaptist groups in Montevideo and Buenos Aires in May–June 1966. Written and delivered when Yoder was only thirty-eight and not yet a full-time faculty member, it is remarkable how fully they anticipate his later work. Clearly he mined them for later writings. The four lectures titled “The Believers Church” may be the best theological introduction available to the Anabaptist/Mennonite tradition. Yoder’s description of the church as a community of forgiveness, discernment, grace; of the mandate to share; and of a morality of participation and community... (shrink)

Physical and chemical processes may act upon the mind; and when we are writing a difficult letter, our mind acts upon our body and, through a chain of physical...

The relation between body and mind is one of the oldest riddles that has puzzled mankind. That material and mental events may interact is accepted even by the law: our mental capacity to concentrate on the task can be seriously reduced by drugs. Physical and chemical processes may act upon the mind; and when we are writing a difficult letter, our mind acts upon our body and, through a chain of physical events, upon the mind of the recipient of the (...) letter. This is what the authors of this book call the 'interaction of mental and physical events'. We know very little about this interaction; and according to recent philosophical fashions this is explained by the alleged fact that we have brains but no thoughts. The authors of this book stress that they cannot solve the body mind problem; but they hope that they have been able to shed new light on it. Eccles especially with his theory that the brain is a detector and amplifier; a theory that has given rise to important new developments, including new and exciting experiments; and Popper with his highly controversial theory of 'World 3'. They show that certain fashionable solutions which have been offered fail to understand the seriousness of the problems of the emergence of life, or consciousness and of the creativity of our minds. In Part I, Popper discusses the philosophical issue between dualist or even pluralist interaction on the one side, and materialism and parallelism on the other. There is also a historical review of these issues. In Part II, Eccles examines the mind from the neurological standpoint: the structure of the brain and its functional performance under normal as well as abnormal circumstances. The result is a radical and intriguing hypothesis on the interaction between mental events and detailed neurological occurrences in the cerebral cortex. Part III, based on twelve recorded conversations, reflects the exciting exchange between the authors as they attempt to come to terms with their opinions. (shrink)

Sir John Hicks is one of the most important and influential economists of the twentieth century. Awarded the Nobel Prize for economics in 1972, he has made contributions across a wide range of economic theory, writing some twenty books. Arguably the most important of these, _Value and Capital_, is seen as the roots of modern microeconomics and general equilibrium theory. Hicks possessed an unusual ability to synthesize the ideas of other economists – something that is evident in his invention (...) of the ‘IS-LM’ diagram to expound Keynes’ General Theory, and is perhaps what he is best known to present day economists for. This two volume set is the second collection on Hicks in this series and includes new assessments of his contributions, covering the last fifteen years. With a new introduction by the editor, this comprehensive and scholarly collection provides students and scholars immediate access to Sir John Hicks’ contributions. (shrink)

John C. Hall; III—Quantity of Pleasure, Proceedings of the Aristotelian Society, Volume 67, Issue 1, 1 June 1967, Pages 35–52, https://doi.org/10.1093/aristotel.